Transcriptional Targeting and MicroRNA Regulation of Lentiviral Vectors
نویسندگان
چکیده
منابع مشابه
Targeting lentiviral vectors to antigen-specific immunoglobulins.
Gene transfer into B cells by lentivectors can provide an alternative approach to managing B lymphocyte malignancies and autoreactive B cell-mediated autoimmune diseases. These pathogenic B cell populations can be distinguished by their surface expression of monospecific immunoglobulin. Development of a novel vector system to deliver genes to these specific B cells could improve the safety and ...
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ژورنال
عنوان ژورنال: Molecular Therapy - Methods & Clinical Development
سال: 2019
ISSN: 2329-0501
DOI: 10.1016/j.omtm.2018.12.013