Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes
نویسندگان
چکیده
منابع مشابه
Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes.
The development, homeostasis, and function of B lymphocytes involve multiple rounds of B-cell receptor (BCR)-controlled proliferation and prolonged maintenance. We analyzed the role of transcription factor Zfx, a recently identified regulator of hematopoietic stem cell maintenance, in B-cell development and homeostasis. Panhematopoietic or B cell-specific deletion of Zfx in the bone marrow bloc...
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ژورنال
عنوان ژورنال: Blood
سال: 2009
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2008-11-188888