Transcranial focused ultrasound generates skull-conducted shear waves: Computational model and implications for neuromodulation
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چکیده
منابع مشابه
Analysis of Transcranial Focused Ultrasound Beam Profile Sensitivity for Neuromodulation of the Human Brain
Analysis of Transcranial Focused Ultrasound Beam Profile Sensitivity for Neuromodulation of the Human Brain Jerel K. Mueller, Wynn Legon, and William J. Tyler* 1 School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA 2 Dept. of Physical Medicine and Rehabilitation, University of Minnesota, Minneapolis, MN 3 School of Biological and Health Systems Engineering, Arizona State...
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Targeted, noninvasive neuromodulation of the brain of an otherwise awake subject could revolutionize both basic and clinical neuroscience. Toward this goal, we have developed nanoparticles that allow noninvasive uncaging of a neuromodulatory drug, in this case the small molecule anesthetic propofol, upon the application of focused ultrasound. These nanoparticles are composed of biodegradable an...
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ژورنال
عنوان ژورنال: Applied Physics Letters
سال: 2020
ISSN: 0003-6951,1077-3118
DOI: 10.1063/5.0011837