Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus
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چکیده
منابع مشابه
Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus
Recent genome-wide association studies (GWAS) have identified variants associated with high-density lipoprotein cholesterol (HDL-C) located in or near the ANGPTL8 gene. Given the extensive sharing of GWAS loci across populations, we hypothesized that at least one shared variant at this locus affects HDL-C. The HDL-C-associated variants are coincident with expression quantitative trait loci for ...
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These are slides for a talk that I gave to the Jackson Lab Center for Genome Dynamics (remotely) on 10 Feb 2015, at the Complex Trait Community meeting in Portland, Oregon, on 11 June 2015, the Department of Biological Statistics and Computational Biology at Cornell University on 18 Apr 2016, and for the Queenstown Research Week conference in Nelson, New Zealand, on 1 Sep 2016, and at the Genet...
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ژورنال
عنوان ژورنال: G3 Genes|Genomes|Genetics
سال: 2017
ISSN: 2160-1836
DOI: 10.1534/g3.117.300088