Tranexamic acid applied topically to achieve haemostasis
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چکیده
منابع مشابه
Systemic Absorption of Topically Applied Salicylic Acid
Salicylic acid was applied topically to the skin of rabbits and humans in order to study the pharmacokinetics of percutaneous absorption, and the effects of formulation and application variables on the rate and extent of absorption. Drug samples incorporated into hydrophilic ointment (USP} and hydrophilic ointment containing 10% urea, were applied to the shaved abdominal areas of female New Zea...
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Topically applied salicylic acid has enjoyed long and extensive usage as an agent to enhance desquamation in various hyperkeratotic skin diseases. In some of these disorders much of the skin surface may be affected, resulting in the potential for significant percutaneous absorption of the drug. We describe a patient who gradually developed evidence of severe salicylate toxicity while being trea...
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Fusidic acid is a bacteriostatic antibiotic that is effective primarily on gram-positive bacteria, such as Staphylococcus and Corynebacterium species. It is often topically applied to the skin, but is also given systemically as a tablet or injection. Allergic contact dermatitis, or urticaria, has been reported as a side effect of fusidic acid treatment, whereas anaphylaxis to topically administ...
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Minoxidil, an orally administered, peripheral vasodilator used to treat hypertension, causes hypertrichosis in more than 80% of users. The drug reduces elevated blood pressure by decreasing peripheral vascular resistance. Chemically, minoxidil i s 2,4-diamino-6-piperidinopyrimidine-3-oxide; it is soluble in water to the extent of approximately 2 mg/ml, i s more readily soluble in propylene glyc...
متن کاملTopically applied azaphenothiazines inhibit contact sensitivity to oxazolone in mice.
In this work we investigated the efficacy of two topically applied azaphenothiazine derivatives, 9-chloro-6-acetylaminobutylquinobenzo[3,2-b][1,4]thiazine (compound 4) and 6-chloroethylureidoethyldiquino[3,2-b;2';3'-e][1,4]thiazine (compound 5), in the amelioration of inflammatory symptoms of contact sensitivity (CS) to oxazolone in mice, in relation to the commercial ointment Protopic® (tacrol...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 2000
ISSN: 0003-2409
DOI: 10.1046/j.1365-2044.2000.01479-17.x