Tramadol HCL: Preformulation Studies of Imperative Part of Formulation Design
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چکیده
منابع مشابه
Formulation and Evaluation of Sustained Release Pellets of Tramadol HCl Using 3 Full Factorial Design
The present research concerns the formulation and evaluation of sustained release pellets filled capsule of opioid analgesic, Tramadol HCl. Development of sustained release dosage form is to maintain therapeutic blood levels of the drug for extended period of time. Sustained release formulation provides uniform concentration at absorption site, maintains plasma concentration within a therapeuti...
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Advent of pharmacology, combinatorial chemistry and High Through Put Screening offered large number of synthetic drugs as a therapeutic substances. These molecules are potent to elucidate their pharmacological activity. However, pharmacokinetic properties of such molecules are rate limiting factors for its safety as well as efficacy. Most of the synthetic drug available so far in market are eit...
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Photostability studies on (±)-tramadol in a liquid formulation.
BACKGROUND Tramadol ((±)-TRA) is recommended for the treatment of mild to moderate cancer pain by the World Health Organization. An oral liquid formulation of (±)-TRA is preferable for patients with a compromised swallowing function. However, the stability of (±)-TRA in aqueous solution has yet to be determined in a clinical setting. The aim of this study was to evaluate the photostability of (...
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ژورنال
عنوان ژورنال: Scholars Academic Journal of Pharmacy
سال: 2020
ISSN: 2347-9531,2320-4206
DOI: 10.36347/sajp.2020.v09i09.002