Tractable Mammalian Cell Infections with Protozoan-primed Bacteria
نویسندگان
چکیده
منابع مشابه
B-Cell Response during Protozoan Parasite Infections
In this review, we discuss how protozoan parasites alter immature and mature B cell compartment. B1 and marginal zone (MZ) B cells, considered innate like B cells, are activated during protozoan parasite infections, and they generate short lived plasma cells providing a prompt antibody source. In addition, protozoan infections induce massive B cell response with polyclonal activation that leads...
متن کاملThe Regulation of CD4+ T Cell Responses during Protozoan Infections
CD4(+) T cells are critical for defense against protozoan parasites. Intracellular protozoan parasite infections generally require the development of a Th1 cell response, characterized by the production of IFNγ and TNF that are critical for the generation of microbicidal molecules by phagocytes, as well as the expression of cytokines and cell surface molecules needed to generate cytolytic CD8(+...
متن کاملImmunology and Molecular Biology of Protozoan Infections
The protozoan parasites, which cause important diseases affecting million of people worldwide especially in the tropical and subtropical areas, are responsible for high mortality and morbidity. Most of these parasites are transmitted by insect vectors and invade a range of different tissues in their mammalian hosts. Prophylactic and therapeutic strategies are far from satisfactory. Indeed, alth...
متن کاملMacrophage Migration Inhibitory Factor in Protozoan Infections
Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. As a general trend, MIF participates in the control of parasite burden at the expense of promoting tissue damage due to increased inflammation.
متن کاملDifferent regulatory mechanisms in protozoan parasitic infections.
The immune response to the protozoan pathogens, Leishmania spp., Trypanosoma spp. and Plasmodium spp., has been studied extensively with particular focus on regulation of the immune response by immunological mechanisms. More specifically, in diseases caused by parasites, immunosuppression frequently prevents immunopathology that can injure the host. However, this allows a small number of parasi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2013
ISSN: 1940-087X
DOI: 10.3791/50300