منابع مشابه
Placental Toxicology of Pesticides
The placenta used to be regarded as an organ protecting the fetus from exposure to toxic chemicals. However, we now know that xenobiotics can cross through the placenta and enter the fetal blood stream (Barr et al., 2007). In addition, some toxicants may accumulate in the placenta and potentially affect its development or function. Therefore, understanding how the placenta affects xenobiotics, ...
متن کاملA computational approach to mechanistic and predictive toxicology of pesticides.
Emerging challenges of managing and interpreting large amounts of complex biological data have given rise to the growing field of computational biology. We investigated the applicability of an integrated systems toxicology approach on five selected pesticides to get an overview of their modes of action in humans, to group them according to their modes of action, and to hypothesize on their pote...
متن کاملA review of Novichok Toxicology
Introduction: Novichoks are considered as the fourth generation of chemical weapons and nerve agents (NA) category. NAs were produced and developed during the Cold War in the (former) Soviet :union:. Due to the confidentiality of the manufacturing process of these agents, there is little information about the properties of these compounds. Like other NA, novichoks are organophosphorus compounds...
متن کاملPharmacology and Toxicology of Leflunomide
Leflunomide (LEF), used for rheumatoid arthritis, inhibits dihydro-orotate dehydrogenase (DHODH) and tyrosine kinase (TK) enzymes and has anti-inflammatory, lymphocyte proliferation regulatory, immunosuppression and chondroprotective effects. The most common adverse effects are gastrointestinal disorders, weight loss, hypertension, skin infection, and neurological and hematological toxicity. It...
متن کاملDetermination of concentration of organophosphate pesticides
Pesticides are used extensively in agricultural lands in Northern provinces of Iran which makes river ecosystems more vulnerable to pesticides pollution. This study was conducted in three river estuaries (Babolrud, Tajanrud and Gorganrud), focusing mainly on the concentration levels of organophosphate pesticides (diazinon, malathion, azinphos-methyl) in the muscle tissue of golden mullet fish, ...
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ژورنال
عنوان ژورنال: Occupational and Environmental Medicine
سال: 1977
ISSN: 1351-0711
DOI: 10.1136/oem.34.2.152