Toxicokinetics of zinc oxide nanoparticles in rats
نویسندگان
چکیده
منابع مشابه
Prenatal development toxicity study of zinc oxide nanoparticles in rats
This study investigated the potential adverse effects of zinc oxide nanoparticles ([ZnO(SM20(+)) NPs] zinc oxide nanoparticles, positively charged, 20 nm) on pregnant dams and embryo-fetal development after maternal exposure over the period of gestational days 5-19 with Sprague-Dawley rats. ZnO(SM20(+)) NPs were administered to pregnant rats by gavage at 0, 100, 200, and 400 mg/kg/day. All dams...
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Biokinetic studies of zinc oxide (ZnO) nanoparticles involve systematic and quantitative analyses of absorption, distribution, metabolism, and excretion in plasma and tissues of whole animals after exposure. A full understanding of the biokinetics provides basic information about nanoparticle entry into systemic circulation, target organs of accumulation and toxicity, and elimination time, whic...
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BACKGROUND Zinc oxide nanoparticles (NZnO) are increasingly used in modern life. Most metal nanoparticles have adverse effects on the liver. AIMS To explore the protective action of curcumin (Cur) against hepatotoxicity induced by NZnO in rats. STUDY DESIGN Animal experimentation. METHODS Control group animals received normal saline, while the Cur group animals were treated with 200 mg/kg...
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A novel technique for glucose sensing using collagen based thin film and zinc oxide (ZnO) nanoparticles, the Zinc Oxide Collagen Glucose Sensor (ZnOCGS) presented here. The Zinc oxide is synthesized using the two medium namely treating with 1.Ethanediol medium (Ethylene glycol) and 2.Water medium. It is characterized using the analytical techniques such as Fourier Transform infrared spectroscop...
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Background: Zinc oxide (ZnO) nanoparticles are used for various industrial and domestic purposes and its release into the environment leads to the adverse effects among humans. This study aimed to evaluate the effect of rat exposure to ZnO nanoparticles on the histopathology of the liver and pancreas tissues, and serum oxidative stress parameters. Methods: Eighty female adult Wistar rats were ...
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ژورنال
عنوان ژورنال: Journal of Physics: Conference Series
سال: 2013
ISSN: 1742-6588,1742-6596
DOI: 10.1088/1742-6596/429/1/012037