Toxicity of orally administered food‐grade titanium dioxide nanoparticles
نویسندگان
چکیده
منابع مشابه
Acute Toxicity of Intravenously Administered Titanium Dioxide Nanoparticles in Mice
BACKGROUND With a wide range of applications, titanium dioxide (TiO₂) nanoparticles (NPs) are manufactured worldwide in large quantities. Recently, in the field of nanomedicine, intravenous injection of TiO₂ nanoparticulate carriers directly into the bloodstream has raised public concerns on their toxicity to humans. METHODS In this study, mice were injected intravenously with a single dose o...
متن کاملToxicity and interaction of titanium dioxide nanoparticles with microtubule protein.
Titanium dioxide (TiO2) nanoparticles (NPs) are widely used in several manufactured products. The small size of NPs facilitates their uptake into cells as well as transcytosis across epithelial cells into blood and lymph circulation to reach different sites, such as the central nervous system. Different studies have shown the risks that TiO2 NPs in the neuronal system and other organs present. ...
متن کاملNasal and Pulmonary Toxicity of Titanium Dioxide Nanoparticles in Rats
In recent decades, titanium dioxide (TiO2) nanoparticles have been used in various applications, including paints, coatings, and food. However, data are lacking on the toxicological aspects associated with their use. The aim of this study was to assess the inhalation toxicity of TiO2 nanoparticles in rats by using inhalation exposure. Male Wistar rats were exposed to TiO2 nanoparticles for 2 we...
متن کاملAcute toxicity of titanium dioxide nanoparticles in Daphnia magna and Pontogammarus maeoticus
Titanium dioxide nanoparticles (nTiO2) are the world's second most widely consumed nanomaterial and large quantities of this material enters the aquatic ecosystem annually. Therefore, understanding the effects of nTiO2 on aquatic organisms is very important. The present study used Daphnia magna as a model freshwater organism and Pontogammarus maeoticus as a brackish water organism to evaluate s...
متن کاملToxicity of colloidal silica nanoparticles administered orally for 90 days in rats
This study was undertaken to investigate the potential toxicity and establish the no observed adverse effect level (NOAEL) and target organ(s) of negatively charged colloidal silica particles of different sizes, ie, SiO2 (EN20(-)) (20 nm) or SiO2 (EN100(-)) 2(100 nm), administered by gavage in Sprague-Dawley rats. After verification of the physicochemical properties of the SiO2 particles to be ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Applied Toxicology
سال: 2020
ISSN: 0260-437X,1099-1263
DOI: 10.1002/jat.4099