Toxicity of antidepressants
نویسندگان
چکیده
منابع مشابه
Toxicity of newer versus older antidepressants
Of all the controversies over the different medi cations used in psychiatry, there is probably least dispute about the effectiveness of antidepressants in controlling depressive illness. However, the choice of which antidepressant to use is bedevilled by the spectre of potential toxicity from adverse effects, interactions and overdose. The unwanted effects may vary from mild and tolerable to po...
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Submit Manuscript | http://medcraveonline.com Abbreviations: TCAs: Tricyclic Antidepressants; SSRIs: Selective Serotonin-Reuptake Inhibitors; MAOIs: Monoamine Oxidase Inhibitors; SNRI: Serotonin-Norepinephrine Reuptake Inhibitor; PMDD: Premenstrual Dysphoric Disorder; SAD: Seasonal Affective Disorder; PMS: Premenstrual Syndrome; NE: Norepinephrine; 5-HT: 5-Hydroxytryptamine; DA: Dopamine; CNS: ...
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BACKGROUND Self-poisoning is a common method of suicide and often involves ingestion of antidepressants. Information on the relative toxicity of antidepressants is therefore extremely important. AIMS To assess the relative toxicity of specific tricyclic antidepressants (TCAs), a serotonin and noradrenaline reuptake inhibitor (SNRI), a noradrenergic and specific serotonergic antidepressant (Na...
متن کاملAcute toxicity of 8 antidepressants: what are their modes of action?
Currently, the hazard posed by pharmaceutical residues is a major concern of ecotoxicology. Most of the antidepressants belong to a family named the Cationic Amphipathic Drugs known to have specific interactions with cell membranes. The present study assessed the impact of eight antidepressants belonging to selective serotonin reuptake inhibitors or serotonin norepinephrine reuptake inhibitors ...
متن کاملAntidepressants, old and new. A review of their adverse effects and toxicity in overdose.
The newer antidepressants are as efficacious as the older agents in the treatment of depression. They have a side effect profile that is different from the older drugs and are generally better tolerated. Drug-drug interactions do exist with some of these agents and can usually be predicted from knowledge of their metabolism. When taken in overdose as the sole agents they are rarely fatal; seizu...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 1989
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.155.3.420a