Toxic Porphyria

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Toxic porphyria.

By ARIF I. CETINGIL AND MUHLIS A. OZEN T HE EXCESSIVE porphyrin excretion seen in idiopathic disturbances of porphyrin metabolism must be differentiated from the porphyrinuria that occurs in various diseases associated with alterations in porphyrin metabolism. Porphyrinuria can he observed in the course of various diseases and may result from the intake of various drugs and poisons. It is well ...

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Porphyria revisited.

IDA MACALPINE and Richard Hunter"2'3 traced four descendants of the Houses of Hanover and Hohenzollern with biochemical evidence of variegate porphyria. They produced a wealth of convincing evidence that the disease afflicted numerous members of these Houses, stretching back from Queen Victoria's father Edward Duke of Kent and Frederick the Great to Margaret Douglas, Countess of Lennox (1515-15...

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Acute Porphyria

PORPHYRIA is a rare disorder of metabolism, in which there is increased production and excretion of uroporphyrin, coproporphyrin, and porphobilinogen.' Despite recent reviews (Goldman and Kaplan (1951), Watson (1951), and Janoff, Poutas, and Young (1953) ), the disease is unfamiliar, but recently there have been an increasing number of case reports. Acute porphyria may present such varied sympt...

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Symptomatic Cutaneous Hepatic Porphyria and from Rats with Porphyria

1. Three tetracarboxylate porphyrins, apart from coproporphyrin, were isolated from the faeces of patients with symptomatic cutaneous hepatic porphyria and of rats with porphyria caused by hexachlorobenzene poisoning. The porphyrins were not present in the urine of the porphyric rats or in the faeces of control rats. 2. Two of the porphyrins were identified as tris-(2-carboxyethyl)-carboxymethy...

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Porphyria cutanea tarda as the most common porphyria.

Porphyrias are an uncommon, heterogeneous group of metabolic diseases caused by inherited or acquired deficiency of specific enzymes in the heme biosynthetic pathway resulting in an excess of porphyrins (red-brown pigments) and their precursors. Accumulation of heme precursors, such as porphyrinogens that are spontaneously oxidized to porphyrins, is responsible for various clinical features. Po...

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ژورنال

عنوان ژورنال: Blood

سال: 1960

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v16.1.1002.1002