Toxic "ictal" confusion in middle age: treatment with benzodiazepines.

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Toxic "ictal" confusion in middle age: treatment with benzodiazepines.

In adult and elderly non-epileptic subjects psychoactive drugs may cause an altered state of consciousness and repetitive irritative EEG discharges. The neurotoxic pathogenesis of this drug-induced confusion and the differentiation from absence status are discussed. Dramatic relief by intravenous benzodiazepines is detailed. Recovery is complete and prognosis is excellent on withdrawal of the o...

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Protracted ictal confusion in elderly patients.

BACKGROUND Ictal confusion, particularly if protracted, often presents a diagnostic challenge. OBJECTIVES To define protracted ictal confusion in elderly patients and to characterize its features and outcome. DESIGN Case series. SETTING Neurology outpatient and emergency departments at 2 tertiary care centers. PATIENTS Consecutive series of 22 ambulatory patients with acute ictal confus...

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Benzodiazepines: toxic serum concentrations in positive enzyme immunoassay responses.

A total of 588 blood specimens collected in an emergency unit were screened for benzodiazepines (BZDs) using enzyme-multiplied immunoassay and gas chromatography. Two-hundred eighty-five samples were positive for BZDs, and 303 samples that were negative by EMIT included 20 samples with BZDs detectable by gas-liquid chromatography. A total of 15 BZDs were identified, and the most frequently occu...

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Side effects of treatment with benzodiazepines.

BACKGROUND The use of benzodiazepine anxiolytics and hypnotics continues to excite controversy. Views differ from expert to expert and from country to country as to the extent of the problem, or even whether long-term benzodiazepine use actually constitutes a problem. Although as a class benzodiazepines act rapidly and are well tolerated, their use presents clinical issues such as dependence, r...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1985

ISSN: 0022-3050

DOI: 10.1136/jnnp.48.5.472