Towards identifying force relaying elastic elements in Drosophila melanogaster NOMPC
نویسندگان
چکیده
Background Sensitive hearing in Drosophila requires the NOMPC (TRPN1) channel. is a bona fide mechano-electrical transduction (MET) channel whose amino-terminal ankyrin repeat (AR) domain consists of 29 ARs. These ARs assemble into helical structure, tether intracellularly to microtubules, and are essential for mechano-gating. Because these findings it was hypothesized that AR might function as “gating spring”, an elastic element relaying forces gate. We report now not gating spring investigate other elements their mechanical properties.
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ژورنال
عنوان ژورنال: Laryngo-rhino-otologie
سال: 2022
ISSN: ['1438-8685', '0935-8943']
DOI: https://doi.org/10.1055/s-0042-1746715