Towards detecting the HER-2 receptor and metabolic changes induced by HER-2-targeted therapies using medical imaging
نویسندگان
چکیده
منابع مشابه
Spontaneous Epithelial-Mesenchymal Transition and Resistance to HER-2-Targeted Therapies in HER-2-Positive Luminal Breast Cancer
Resistance to trastuzumab, a rationally designed HER-2-targeting antibody, remains a major hurdle in the management of HER-2-positive breast cancer. Preclinical studies suggest the mechanisms of trastuzumab resistance are numerous. Unfortunately, the majority of these studies are based around HER-2-positive (HER-2+) luminal cell lines. The role of epithelial to mesenchymal transition (EMT), a g...
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ژورنال
عنوان ژورنال: The British Journal of Radiology
سال: 2010
ISSN: 0007-1285,1748-880X
DOI: 10.1259/bjr/31053812