Towards Cardio-Precision medicine

Towards Cardio-Precision medicine.

Tensor Factorization towards Precision Medicine

Precision medicine initiatives come amid the rapid growth in quantity and variety of biomedical data, which exceeds the capacity of matrix oriented data representations and many current analysis algorithms. Tensor factorizations extend the matrix view to multiple modalities and support dimensionality reduction methods that identify latent groups of data for meaningful summarization of both feat...

Towards precision medicine in epilepsy surgery.

Up to a third of all patients with epilepsy are refractory to medical therapy even in the context of the introduction of new antiepileptic drugs (AEDs) with considerable advantages in safety and tolerability over the last two decades. It has been widely accepted that epilepsy surgery is a highly effective therapeutic option in a selected subset of patients with refractory focal seizure. There i...

Synthetic human leukemia models: towards precision medicine

Towards precision medicine for sepsis patients

Over the last decade it has become clear that the immunological response and clinical course in sepsis patients is too complex to simply regard it as ‘hyperinflammation-induced organ failure’. In contrast to the previous belief that patients mainly suffer from an exaggerated pro-inflammatory response, it has now become evident that a proand anti-inflammatory response are mounted simultaneously ...