Total Synthesis of a Tetracyclic Anti-tumor, UCE6.
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چکیده
منابع مشابه
Studies towards the total synthesis of lycoposerramine A. Synthesis of a model for the tetracyclic core.
Lycoposerramine A (1) is a pentacyclic alkaloid isolated in 2001 by Takayama and co-workers. A concise synthesis of a model compound 8 for the tetracyclic core of this natural product is described. Key steps include the desymmetrising free-radical cyclisation of compound 7 to give compound 18 and spirocyclisation of compound 26 to give compound 8. Earlier approaches using a novel high-yielding ...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 2002
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.55.1076