Torsades de pointes complicating treatment with terodiline.

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[Torsades de pointes during methadone treatment].

Methadone is a synthetic opioid that has been used successfully to treat heroin addiction and chronic pain. It is usually well tolerated and has few side effects. Recently, an association with torsade de pointes has been reported. We present 4 cases of torsade de pointes during methadone treatment.

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Torsades de Pointes During Methadone Treatment

Four patients (3 men, 1 woman) with no known history of heart disease were seen in the emergency room for syncopal episodes (Table). All were under longterm methadone therapy, although only 1 was receiving >200 mg/day. Three of these patients were infected with human immunodeficiency virus (HIV), but only 1 was on antiretroviral therapy. The electrocardiographic recordings and monitoring showed...

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Torsades de Pointes (TdP) after Taking Prenylamine

L'intervalle de temps variable existante entre le debut du traitement par la prenylamine et la sur­venu de toisade de pointe et d'autre oart la raretee de· telle camplication est considere par les auteurs c0mme une indice de !'intervention de d'autres fac­teurs, parmie Jes quelles, la perturbation electroly­tique doit jouer le role principal. 

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[Torsades de pointes associated with rupatadine].

Torsades de pointes (TdP) tachycardia is a rare polymorphic ventricular tachycardia characterized by short, self-limiting runs, and a prolonged QT interval, which can deteriorate into persistent ventricular fibrillation and sudden death. This arrhythmia is gaining importance, since it is known to be related to commonly prescribed drugs and electrolyte abnormalities. Most of the drugs that induc...

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Methadone-induced Torsades de pointes.

Torsades de pointes is a polymorphic ventricular tachycardia that can quickly evolve into ventricular fibrillation and sudden death. This arrhythmia often occurs secondary to medication- induced cardiac repolarization dysfunction with resultant prolonged QTc interval on ECG. Numerous medications can predispose patients to this deadly tachycardia. We report a case of methadone-induced Torsades d...

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ژورنال

عنوان ژورنال: BMJ

سال: 1991

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.302.6790.1469-c