Too hungry to sleep

Hippo - hungry, hungry for melanoma invasion

The acquisition of invasive properties in melanoma is associated with a high proclivity for metastasis, but the underlying pathways are poorly characterized. The Hippo pathway has an important role in organ size control and is dysregulated in some type of tumors. The present study, "Pro-invasive activity of the Hippo pathway effectors YAP and TAZ in cutaneous melanoma" by Nallet-Staub et al., 2...

Too much or too little sleep can lead to coronary heart disease

How much sleep apnea is too much?

Events of breathing interruption are universally observed during sleep. Togo and colleagues [1], in a study to identify respiratory and movement sleep disorders in chronic fatigue syndrome (CFS) patients with and without fibromyalgia (FM), employed an apnea-hypopnea index (AHI) of 18 events per hour as the normal limit and reported an absence of diagnosable sleep-disordered breathing (SDB). The...

Hungry Flies Tune to Vinegar

Many molecular signals that represent hunger and satiety in the body have been identified, but relatively little is known about how these factors alter the nervous system to change behavior. Root et al. (2011) report that hunger modulates the sensitivity of specific olfactory sensory neurons in Drosophila and facilitates odor-search behavior.

Sleep apnoea syndrome--a too frequent misdiagnosis.

Sir, A 45 year old woman, experienced progressive deterioration of memory, loss of concentration, anxiety, tiredness, insomnia with nightmares and arousals characterized by unexplained fear and, rarely, thoughts of suicide. She developed a profound depression, so that 2 months later in November 1987 she decided to discontinue herjob in the stock market. A diagnosis of menopausal-related anxious...