Tolerance and Residue Study for Standardized Macleaya cordata Extract Added to Chicken Feed
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چکیده
منابع مشابه
Macleaya cordata extract and Sangrovit genotoxicity. Assessment in vivo.
BACKGROUND Sanguinarine (SG) has been reported to form DNA adducts in vitro and increase the levels of DNA single strand breaks in the blood and bone marrow of mice treated intraperitoneally with SG. Recently, we showed no genotoxic effects of orally administrated 120 mg/kg feed Macleaya cordata extract (a mixture of sanguinarine and chelerythrine) in pigs or rats in 90-day studies. The goal of...
متن کاملMacleaya cordata Extract Decreased Diarrhea Score and Enhanced Intestinal Barrier Function in Growing Piglets
Macleaya cordata extract is of great scientific and practical interest to researchers, due to its antimicrobial and anti-inflammatory responses within experimental animals. This study was designed to determine the diarrhea score and innate immunity of growing piglets after they had received Macleaya cordata extract supplements. A total of 240 growing pigs were randomly assigned to one of three ...
متن کاملMacleaya cordata Extract Reduces Inflammatory Responses of Intestinal Epithelial Cells in Vitro
Background: The EU ban on antimicrobial growth promoters (AGP) has initiated a search for nonantibiotic alternatives. It has been demonstrated that certain antibiotics and non-antibiotic alternatives enhance growth by inhibiting inflammatory cells, i.e. neutrophils and macrophages in the intestine. There is very little information on the effect of anti-inflammatory compounds on intestinal epith...
متن کاملGrowth promotion in broilers by both oxytetracycline and Macleaya cordata extract is based on their anti-inflammatory properties.
The non-antibiotic anti-inflammatory theory of antimicrobial growth promoters (AGP) predicts that alternatives can be selected by simple in vitro tests. In vitro, the known AGP oxytetracycline (OTC) and a Macleaya cordata extract (MCE) had an anti-inflammatory effect with a half-maximal inhibitory concentration of 88 and 132 mg/l, respectively. In vivo, chickens received three different concent...
متن کاملIntegration of Transcriptome, Proteome and Metabolism Data Reveals the Alkaloids Biosynthesis in Macleaya cordata and Macleaya microcarpa
BACKGROUND The Macleaya spp., including Macleaya cordata and Macleaya microcarpa, are traditional anti-virus, inflammation eliminating, and insecticide herb medicines for their isoquinoline alkaloids. They are also known as the basis of the popular natural animal food addictive in Europe. However, few studies especially at genomics level were conducted on them. Hence, we performed the Macleaya ...
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ژورنال
عنوان ژورنال: International Journal of Poultry Science
سال: 2014
ISSN: 1682-8356
DOI: 10.3923/ijps.2014.368.373