Tocilizumab for polymyalgia rheumatica: a first or second line?
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منابع مشابه
Tocilizumab for polymyalgia rheumatica: a first or second line?
To the Editor: In the open-label uncontrolled trial recently published in the Annals of the Rheumatic Diseases, Devauchelle-Pensec et al showed high efficacy of tocilizumab as a first-line treatment for polymyalgia rheumatica (PMR). Twenty patients with PMR were treated with three tocilizumab intravenous infusions at a dose of 8 mg/kg with 4-week intervals followed by oral prednisone. At 12 wee...
متن کاملUpdate on polymyalgia rheumatica.
Polymyalgia rheumatica is an inflammatory disease of unknown etiology affecting individuals aged fifty years and older, mainly of Caucasian ethnicity. Polymyalgia rheumatica is associated with giant cell arteritis more frequently than expected by chance alone. In both conditions, females are affected two to three times more often than males. The clinical hallmark manifestations of polymyalgia r...
متن کاملA disease activity score for polymyalgia rheumatica.
OBJECTIVE To develop a composite score for measurement of disease activity in polymyalgia rheumatica (PMR) and assess its internal and external validity. METHODS A PMR activity score (AS) was designed and assessed for internal and external validity in two patient cohorts: 57 international patients evaluated primarily for development of the PMR-AS at baseline, weeks 4 and 24; and for validatio...
متن کاملPolymyositis, not polymyalgia rheumatica.
The distinction between polymyalgia rheumatica and polymyositis is important for treatment and prognosis. Four elderly patients were diagnosed and treated for polymyalgia: raised creatine kinase led to muscle biopsy and a diagnosis of polymyositis.
متن کامل[Conditions mimicking polymyalgia rheumatica].
OBJECTIVE To examine the main clinical and laboratory data of patients initially diagnosed with polymyalgia rheumatica (PMR), which then developed another conditions. MATERIAL AND METHODS We reviewed the clinical records of patients diagnosed with PMR in three hospitals in Argentina. Patients had a diagnosis of PMR if they met the following criteria: age ≥ 50 years, erythrocyte sedimentation ...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2016
ISSN: 0003-4967,1468-2060
DOI: 10.1136/annrheumdis-2016-209596