Tiny brakes for a growing heart

Heart Failure: A Growing Problem

Heart Failure: A Growing Problem With 550 000 new cases diagnosed annually and $37 billion spent per year, heart failure (HF) with reduced ejection fraction is one of the largest contributors to disease burden and healthcare expenditure in the United States. Despite significant progress in the treatment of HF with medications, the prognosis of HF remains dismal, with a mortality rate of 42% at ...

RGS Proteins in Heart: Brakes on the Vagus

It has been nearly a century since Otto Loewi discovered that acetylcholine (ACh) release from the vagus produces bradycardia and reduced cardiac contractility. It is now known that parasympathetic control of the heart is mediated by ACh stimulation of G(i/o)-coupled muscarinic M2 receptors, which directly activate G protein-coupled inwardly rectifying potassium (GIRK) channels via Gβγ resultin...

Use of Palm Waste Cellulose as a Substitute for Common Growing Media in Aglaonema Growing

In order to evaluate the possibility use of palm waste cellulose as a substitute substrate for growing pot plants, an experiment was conducted in completely randomized block design with 6 replication and six treatments on Aglaonema sp. The treatments were 5 levels including 0, 25, 50, 75 and 100 palm celluloid wastes mixed with different rates of some amendments such as peat, coconut coir, perl...

Heart failure-a growing epidemic in Asia.

Adult congenital heart disease: a growing epidemic.

Medical and surgical breakthroughs in the care of children born with heart defects have generated a growing population of adult survivors and spawned a new subspecialty of cardiology: adult congenital heart disease. The prevalence of adult congenital heart disease is escalating at a rampant rate, outpacing the relatively static prevalence of pediatric congenital heart disease, because adults no...