Tinospora cordifolia attenuates antipsychotic drug induced hyperprolactinemia in Wistar rats
نویسندگان
چکیده
منابع مشابه
Modulatory effect of Tinospora cordifolia extract on Cd-induced oxidative stress in Wistar rats
BACKGROUND Cadmium (Cd), a nonessential heavy metal, is a major environmental and public health concern. Oxidative stress plays an important role in Cd-induced kidney dysfunction. Tinospora cordifolia, a medicinal plant rich in phytochemicals, possesses antioxidant activity. The objective of the present study was to assess the protective effect of Tinospora cordifolia-stem methanolic extract (T...
متن کاملAntipsychotic-induced hyperprolactinemia.
Use of antipsychotic agents has been associated with hyperprolactinemia, or elevated prolactin levels; this hormonal abnormality can interfere with the functioning of reproductive, endocrine, and metabolic systems. As antipsychotic agents are increasingly used for both United States Food and Drug Administration-approved and nonapproved indications, many individuals are at risk for developing an...
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Many plants are claimed to possess antidiabetic and antioxidant activity. In practice, it is being increasingly recognized to be an alternative approach to modern medicine. This study assess the antioxidant capacity of Tinospora cordifolia stem methanol extract in daily oral administration of 500 mg/kg of body weight for 40 days in alloxan induced diabetic rats. The erythrocytes membrane lipid ...
متن کاملPhytochemical analysis and hepatoprotective properties of Tinospora cordifolia against carbon tetrachloride-induced hepatic damage in rats
The present study was conducted to evaluate the hepatoprotective activity of different extracts of Tinospora cordifolia against carbon tetrachloride (CCl4) induced liver damage in rats. The pet ether, ethanol and aqueous extracts of various parts of the plant such as leaf, stem and root were tested at the dose of 200mg/kg body weight orally using Wistar albino rats and Silymarin was given as re...
متن کاملAntipsychotic-induced Hyperprolactinemia: Pathophysiology and Clinical Consequences
Hyperprolactinemia is one of the major adverse effects of antipsychotic agents. Although it is predominantly associated with the use of conventional or typical agents, atypical agents also cause varying degrees of hyperprolactinemia. Clinical manifestations, which tend to be underrecognized, are the result of the direct action of prolactin on its target tissues and of the sequelae of hypogonadi...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Reproduction
سال: 2019
ISSN: 2305-0500
DOI: 10.4103/2305-0500.259171