Time-resolved fluorescence of bacteriophage Pf1 DNA-binding protein. Determination of oligonucleotide and polynucleotide binding parameters
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چکیده
منابع مشابه
Investigation and Determination the Binding Site of Glycyrrhizin of Liquorice to DNA
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چکیده با توسعه شهر نشینی و دخل و تصرف غیر مجاز در حریم رودخانه ها خسارات زیادی به رودخانه و محیط زیست اطراف آن وارده می شود. در حال حاضر بر اساس آئین نامه اصلاح شده بستر و حریم رودخانه ها، حریم کمی رودخانه که بلافاصله پس از بستر قرار می گیرد از 1 تا20 متر از منتهی الیه طرفین بستر رودخانه تعیین، که مقدار دقیق آن در هر بازه از رودخانه مشخص نیست. در کشورهای دیگر روشهای متفاوتی من جمله: درصد ریسک...
15 صفحه اولMapping the interactions of the single-stranded DNA binding protein of bacteriophage T4 (gp32) with DNA lattices at single nucleotide resolution: polynucleotide binding and cooperativity
We here use our site-specific base analog mapping approach to study the interactions and binding equilibria of cooperatively-bound clusters of the single-stranded DNA binding protein (gp32) of the T4 DNA replication complex with longer ssDNA (and dsDNA) lattices. We show that in cooperatively bound clusters the binding free energy appears to be equi-partitioned between the gp32 monomers of the ...
متن کاملComparative Investigation of R213G Mutation in DNA-Binding Domain of P53 Protein via Molecular Dynamics Simulation
Introduction: P53 is a tumor suppressor protein with numerous missense mutations identified in its gene. These mutations are observed in a vast number of cancers. R213G is one of them which has a role in metastatic lung cancers. In this research, R213G was studied in comparison with the wild type via molecular dynamics simulation. Method: For the three-dimensional structure of the wild-type P53...
متن کاملComparative Investigation of R213G Mutation in DNA-Binding Domain of P53 Protein via Molecular Dynamics Simulation
Introduction: P53 is a tumor suppressor protein with numerous missense mutations identified in its gene. These mutations are observed in a vast number of cancers. R213G is one of them which has a role in metastatic lung cancers. In this research, R213G was studied in comparison with the wild type via molecular dynamics simulation. Method: For the three-dimensional structure of the wild-type P53...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1985
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1985.tb08897.x