Thyroid hormones and fetal neurological development
نویسندگان
چکیده
منابع مشابه
Thyroid hormones and fetal neurological development.
The development of fetal thyroid function is dependent on the embryogenesis, differentiation, and maturation of the thyroid gland. This is coupled with evolution of the hypothalamic-pituitary-thyroid axis and thyroid hormone metabolism, resulting in the regulation of thyroid hormone action, production, and secretion. Throughout gestation there is a steady supply of maternal thyroxine (T(4)) whi...
متن کاملThyroid Hormones and Fetal Development
The importance of thyroid hormones for normal fetal development is well established. Through animal experiments (1,2) and clinical studies (3,4), thyroid hormones have been clearly found to be crucial in brain development, maturation, and normal function. The fetal thyroid begins to produce thyroid hormones at about 10 to 12 weeks of gestation. During the first trimester, thyroid hormones are s...
متن کاملThyroid Hormones and Motoneurons Development
It is well known that postnatal maturation of the central nervous system is critically dependent on thyroid hormone levels (Thompson & Potter, 2000) and this might influence the neuromuscular system (Barakat-Walter et al., 2000). Previous neuroanatomical and biochemical investigations demonstrated that development of skeletal muscles including the masseter is affected by both neuronal and thyro...
متن کاملThyroid hormones in fetal growth and prepartum maturation.
The thyroid hormones, thyroxine (T4) and triiodothyronine (T3), are essential for normal growth and development of the fetus. Their bioavailability in utero depends on development of the fetal hypothalamic-pituitary-thyroid gland axis and the abundance of thyroid hormone transporters and deiodinases that influence tissue levels of bioactive hormone. Fetal T4 and T3 concentrations are also affec...
متن کاملThyroid hormones states and brain development interactions.
The action of thyroid hormones (THs) in the brain is strictly regulated, since these hormones play a crucial role in the development and physiological functioning of the central nervous system (CNS). Disorders of the thyroid gland are among the most common endocrine maladies. Therefore, the objective of this study was to identify in broad terms the interactions between thyroid hormone states or...
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ژورنال
عنوان ژورنال: Journal of Endocrinology
سال: 2011
ISSN: 0022-0795,1479-6805
DOI: 10.1530/joe-10-0444