Thymidine- and AZT-linked 5-(1,3-dioxoalkyl)tetrazoles and 4-(1,3-dioxoalkyl)-1,2,3-triazoles

DRAFT v 4 5 / 13 / 06 ( Final

Of my own situation I wrote: “In one day I typically receive 5-10 pieces of regular junk mail, 15-25 regular letters, 5 pieces of campus mail, 5 reports or documents (not all technical), 5-10 incoming phone calls, 10-20 local electronic messages, and 10-20 external electronic messages. Although many of these messages are discarded or forwarded to others for handling, much of my time is required...

Cover for Volume.13, No.4

Cover vol. 13, no. 5, October 2016

5-Benzoyl-13-bromo-4-hy­droxy[2.2]paracyclo­phane

The title compound, C(23)H(19)BrO(2), was synthesized from 13-bromo-4-hy-droxy[2.2]paracyclo-phane and benzoyl chloride. The hy-droxy and carbonyl groups are involved in intra-molecular O-H⋯O hydrogen bonding. The crystal packing exhibits weak C-H⋯O inter-actions, which link the mol-ecules into sheets parallel to the bc plane.

Transplacental Passage of Interleukins 4 and 13?

The mechanisms by which prenatal events affect development of adult disease are incompletely characterized. Based on findings in a murine model of maternal transmission of asthma risk, we sought to test the role of the pro-asthmatic cytokines interleukin IL-4 and -13. To assess transplacental passage of functional cytokines, we assayed phosphorylation of STAT-6, a marker of IL-4 and -13 signali...