منابع مشابه
Regulation of IGFBP-1 in Metabolic Diseases
Insulin-like growth factor binding proteins (IGFBPs) play a key role in insulin and insulin growth factor signaling and are known to be expressed in several tissues. Studies on the transcriptional regulation of IGFBP genes in various cell types have suggested that IGFBPs control both systemic hormones and regulators. Also, the complex regulatory mechanisms involved in both transcription and tra...
متن کاملE2F-1 Directly Regulates Thrombospondin 1 Expression
Thrombospondin 1 (TSP1) has been shown to play a critical role in inhibiting angiogenesis, resulting in inhibition of tumor growth and metastases. To figure out TSP1's regulators will lead to reveal its biological function mechanistically. In this study, we show that E2F-1 could activate the transcription of TSP1 by both promoter assays and Northern blot. Analysis of various TSP1 promoter mutan...
متن کاملMetabolic Diseases in Children
(Reading of Chairman Najjar’s paper.) Chairman Mallar.’ I have indicated to you that the alpha cells of the pancreas excrete the hyperglycemic factor. The practical value of this finding can only be measured by its possible hearing on the understanding and treatment of aberrations of carbohydrate metabolism. Dr. Irvine McQuarnie has lately found cases of hypoglycemia that showed absence of thes...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2021
ISSN: 1664-2392
DOI: 10.3389/fendo.2021.638536