منابع مشابه
Fertility Preservation in Gynecological Cancers
For cancers of reproductive system in women, fertility preservation is complex. Fertility is also affected by therapies, however prevention is possible. Radiotherapy affects gonads, uterus, and subsequent pregnancy outcomes in all ages. However, degree and damage depend on dose, irradiation field, and age at the time of exposure. Ovarian transposition is considered if ovarian involvement is unl...
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Gynecologic cancers are the unregulated growth of neoplastic cells that arise in the cervix, ovaries, fallopian tubes, uterus, vagina, and vulva. Although gynecologic cancers are characterized by different signs and symptoms, studies have shown that they share common risk factors, such as smoking, obesity, age, exposure to certain chemicals, infection with human immunodeficiency virus (HIV), an...
متن کاملOncogenic BARD1 isoforms expressed in gynecological cancers.
BARD1 is required for protein stability and tumor suppressor functions of BRCA1, which depend on the ubiquitin ligase activity of the BRCA1-BARD1 heterodimer. The NH(2)-terminal RING domains of both proteins act as interaction modules and form a ubiquitin ligase, which has functions in DNA repair, cell cycle checkpoint regulation, and mitosis. Interestingly, up-regulated expression of truncated...
متن کاملHistopathological Study of Gynecological Cancers in Patients Admitted to Baqiyatallah Hospital in Tehran during 2011-2019
Background and Objective: Each type of cancer has its own histopathological findings that determine the type of treatment regimen and the course of the disease. The present study aimed to histopathologically determine the types of gynecological cancers in patients admitted to Baqiyatallah Hospital over a nine-year period. Materials and Methods: This retrospective study was conducted based on h...
متن کاملUrinary tract dysfunctions after gynecological cancers treatment
Oncological treatment results in a series of major adverse effects, local and systemic, depending on the type of treatment – surgery, radiotherapy (RT), chemotherapy (CT) or a combination of those. Chemotherapy acts mainly systemically, but drugs used during treatment are eliminated through the urinary tract, often unmetabolized, and come in direct contact with the epithelium of the bladder, ur...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Therapeutics
سال: 2017
ISSN: 0973-1482
DOI: 10.4103/0973-1482.189234