THREONINE, ISOLEUCINE, AND ISOLEUCINE-VALINE MUTANTS OF SALMONELLA TYPHIMURIUM
نویسندگان
چکیده
منابع مشابه
Isoleucine - Valine Requiring Mutants of Salmonella Typhimurium
E have isolated a number of mutant strains of Salmonella typhimurium that display a marked inhibition of growth when valine is added to minimal medium. Attempts to elucidate the nature of the mutation(s) in these valinesensitive strains have included enzymatic and transductional analyses, as well as growth studies, on four of these strains. The results of these studies are presented and discuss...
متن کاملIsoleucine-valine Requiring Mutants of Salmonella Typhimurium.
initial reports on the mutant strains of Salmonella typhimurium that T: eui r both isoleucine and valine for growth (ilva strains) were published concomitantly by GLANVILLE and DEMEREC ( 1960) and WAGNER and BERGQUIST (1960). These studies showed that although the available ilva strains could be divided into four complementation groups ( A , B , C and D ) on the basis of abortive transduction r...
متن کاملIsoleucine-valine requiring mutants of Salmonella typhimurium. II. Strains deficient in dihydroxyacid dehydratase activity.
MONG the available isoleucine-valine requiring strains of Salmonella t yphiA murium (termed ilu) are a number of mutants deficient in CY, p-dihydroxyacid dehydratase4 activity (ARMSTRONG and WAGNER 1964). The production of this enzyme is under the control of the iluD gene (WAGNER and BERGQUIST 1960). This report is concerned with transductional analyses that have been carried out using the iZuD...
متن کاملThreonine, isoleucine, valine and leucine requirements of the young kitten.
Growth assays and nitrogen balance trials were conducted in an attempt to estimate requirements for threonine, isoleucine, valine and leucine. Weanling kittens were fed a basal purified diet containing 27% crystalline L-amino acids and 4,700 kcal metabolizable energy per kilogram diet. Based upon rate and efficiency of growth, and upon urinary nitrogen excretion, estimated requirements for thre...
متن کاملBiosynthesis of Valine and Isoleucine
The isotope studies of Strassman et al. (3, 4) first implicated cu-acetolactate and cu-aceto-cY-hydroxybutyrate as biosynthetic precursors of valine and isoleucine, respectively. The observed accumulation of acetolactate by Escherichia coli (5, 6) and of the decarboxylation products of acetolactate and acetohydroxybutyrate by Neurospora crassa (7) when mutants of these organisms are grown with ...
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ژورنال
عنوان ژورنال: Genetics
سال: 1960
ISSN: 1943-2631
DOI: 10.1093/genetics/45.10.1359