Three-week versus four-week schedule of cisplatin and gemcitabine: results of a randomized phase II study
نویسندگان
چکیده
منابع مشابه
A three-week schedule of gemcitabine-cisplatin in advanced non-small-cell lung cancer with two different cisplatin dose levels: a phase II randomized trial.
BACKGROUND To explore a new schedule of gemcitabine-cisplatin (GP) combination therapy using two different cisplatin doses in patients with advanced non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS From May to December 1997, 92 chemonaive patients entered the study and 88 (28 with locally advanced and 60 with disseminated NSCLC) were evaluable for response and toxicity (45 in arm A an...
متن کاملGemcitabine-cisplatin: a schedule finding study.
PURPOSE To evaluate the tolerability of four alternating cisplatin-gemcitabine schedules. A secondary aim was to evaluate the clinical efficacy of this combination. PATIENTS AND METHODS Forty-one patients with advanced solid tumors received alternating sequences with a 4- and 24-hour interval of cisplatin and gemcitabine. Gemcitabine 800 mg/m2 was administered as a 30-min infusion on day 1, 8...
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این تحقیق کوشیده است با انتخاب پنج رمان از میان آثار برگزیده، «چارلز دیکنز»، «جورج الیوت» و «توماس هاردی » و با رویکردی تطبیقی به بررسی درونمایه ی «ازدواج» در آثار این سه رمان نویس بزرگ دوره ی ویکتوریا بپردازد. فرضیه ی اولیه ی تحقیق این بوده است که چارلز دیکنز (1870- 1812) با زبانی شوخ و گزنده، جورج الیوت(1880- 1819) با نگاهی آموزشی–اندرزگونه و توماس هاردی(1928- 1840) با رویکردی تلخ وانتقادی به...
phase ii study of gemcitabine and cisplatin in advanced non-small cell lung cancer
cisplatin-based chemotherapy is the standard treatment for advanced non-small cell lung cancer (nsclc). many novel drugs have been used in combination with cisplatin in this setting. of these drugs, gemcitabine is reported to have a high response rate and acceptable toxicity. the aim of this study was to evaluate the efficacy and safety of gemcitabine and cisplatin combination. twentythree pati...
متن کاملphase ii study of gemcitabine and cisplatin regimen in advanced non-small cell lung cancer (nsclc).
background: cisplatin-based chemotherapy is the standard treatment for advanced non-small cell lung cancer (nsclc). many novel drugs, including gemcitabine, vinorelbine, paclitaxel and docetaxel have been used in combination with cisplatin in this setting. of these drugs, gemcitabine is reported to have a high response rate and acceptable toxicity. the aim of this study was to evaluate the effi...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2002
ISSN: 0923-7534
DOI: 10.1093/annonc/mdf186