Third-Generation SERMs May Face Uphill Battle

The Uphill Battle of Ant Programming Vs. Genetic Programming

Ant programming has been proposed as an alternative to Genetic Programming (GP) for the automated production of computer programs. Generalized Ant Programming (GAP) – an automated programming technique derived from principles of swarm intelligence – has shown promise in solving symbolic regression and other hard problems. Enhanced Generalized Ant Programming (EGAP) has improved upon the perform...

Encouraging learning how to fish: an uphill but worthwhile battle.

INTRODUCTION Encouraging teaching practices such as problem-based learning (PBL) amongst undergraduate students within a lecture-based, system-based integrated curriculum is a challenge. Students are apprehensive about developing an organised framework for acquiring knowledge while lecturers are required to reframe their views on the educational process and their role as educators. MATERIALS ...

Game-theoretic recommendations: some progress in an uphill battle

Game theory has become the central language for the analysis of multi-agent systems. Moreover, the central gametheoretic solution concept, the Nash equilibrium, has become a standard tool for that analysis. A game is a general way for representation of interactions among agents: each agent has strategies he can choose from, and each tuple of strategies, one for each agent, determines a payoff f...

The uphill battle to find new TB treatments.

On Jan 17, 2017, Médecins Sans Frontières (MSF) enrolled the first patient in the TB PRACTECAL trial. The phase 2b/3 trial is scheduled to recruit 630 patients with rifampicinresistant, multi-drug resistant (MDR), and extensively drug-resistant (XDR) tuberculosis in Belarus, South Africa, and Uzbekistan. The first stage will test three 6-month regimens based on the new drugs bedaquiline and pre...

Uphill battle: The saga of hCG research that led to a paradigm shift