منابع مشابه
Thinking big with small molecules
Synthetic chemistry has enabled scientists to explore the frontiers of cell biology, limited only by the laws of chemical bonding and reactivity. As we investigate biological questions of increasing complexity, new chemical technologies can provide systems-level views of cellular function. Here we discuss some of the molecular probes that illustrate this shift from a "one compound, one gene" pa...
متن کاملScale: Thinking Big
The International Labour Office welcomes such applications. Libraries, institutions and other users registered with reproduction rights organizations may make copies in accordance with the licences issued to them for this purpose. Visit www.ifrro.org to find the reproduction rights organization in your country. The designations employed in ILO publications, which are in conformity with United N...
متن کاملSystems Thinking and Agility; Think Big, Act Small - logo TBD
The focus in agile methods is on useful and feasible increments. The architecture is evolving by refactoring. Refactoring steps are only taken if needed for the increment. The longer term result of this approach is an emerging architecture, where every small step makes sense, but the overall architecture is not satisfying. In this article we propose a time-boxed investment to create the big pic...
متن کاملVisualizing coronary atherosclerosis in vivo: thinking big, imaging small.
Over the past decade, a keen interest has developed in the imaging of atherosclerosis in patients in vivo. One approach is the direct intracoronary visualization with ultrasound, angioscopy, or more recently, magnetic resonance imaging (MRI). Another, more practical approach is non-invasive imaging with ultrasound, MRI, or radionuclide tracers. In this issue of the Journal, Hamilton et al. (1) ...
متن کاملThinking Big About Tiny Databases
Work on early tiny database systems, like TinyDB [17] and Cougar [23] has shown that a declarative approach can provide a powerful and easy to use interface for collecting data from static sensor networks. These early systems, however, have significant limitations; in particular, they are useful only for low-rate data collection applications on static sensor networks and they don’t integrate we...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 1987
ISSN: 0028-0836,1476-4687
DOI: 10.1038/326900a0