Think big — think omics

Brain Projects Think Big

BIG BANG HUMAN BRAIN The universe started with the Big Bang some 13,500 million (billion) years ago. Then very recently, about 200,000 years ago, another " Big Bang " happened – Homo sapiens appeared on earth. It has many genetic similarities with other species such as the chimpanzee and, even more so, with other hominids such as the Neanderthals who lived with us until 30,000 or so years ago. ...

Think Big, from Voice to Lim

We will test the efficacy of an innovative physical therapy treatment technique based upon the Lee Silverman Voice Treatment (LSVT). Thus, people with PD will undergo intensive practice of high effort/large amplitude arm movements while focusing on the sensory awareness of “movement bigness.” As LSVT uses extensive practice and feedback/knowledge of results to teach patients the amount of effor...

Think big--giant genes in bacteria.

Long genes should be rare in archaea and eubacteria because of the demanding costs of time and resources for protein production. The search in 580 sequenced prokaryotic genomes, however, revealed 0.2% of all genes to be longer than 5 kb (absolute number: 3732 genes). Eighty giant bacterial genes of more than 20 kb in length were identified in 47 taxa that belong to the phyla Thermotogae (1), Ch...

European genomics: think big or small?

With the first draft of the human genome completed, Michael Gross looks at some of the plans to study a variety of European populations to exploit the new information.

Time to think big in human biology?