منابع مشابه
Thiazolidinediones and Edema: Recent Advances in the Pathogenesis of Thiazolidinediones-Induced Renal Sodium Retention
Thiazolidinediones (TZDs) are one of the major classes of antidiabetic drugs that are used widely. TZDs improve insulin resistance by activating peroxisome proliferator-activated receptor gamma (PPARγ) and ameliorate diabetic and other nephropathies, at least, in experimental animals. However, TZDs have side effects, such as edema, congestive heart failure, and bone fracture, and may increase b...
متن کاملFluid Retention Produced by Guanethidine
IN a previous paper,1 the clinical features of fluid retention complicating the use of guanethidine were discussed. Of 134 patients treated continuously for over a year, 44 (32.8 per cent) were observed to retain fluid and yet, comparing these with the 90 who apparently avoided the complication, no significant differences could be found in respect to age, previous renal disease, change in the f...
متن کاملFluid Retention Syndrome in Women
The term Fluid Retention Syndrome (abbreviated; FRS) is more accurate than the commonly used term “idiopathic edema “or “cyclical edema “, as it substantiates the view that the disorder has multifactorial etiology. FRS of women may be defined as fluid retention occurring in the absence of well-defined hydrostatic or oncotic mechanism as a result of congestive cardiac failure, hypoproteinemia or...
متن کاملThiazolidinediones and liver toxicity.
Thiazolidinediones or glitazones specifically target insulin resistance. They have proven efficacy for reducing plasma glucose levels of type 2 diabetic patients treated with diet alone, sulphonylureas, metformin or insulin. In addition, they may be associated to some improvement of cardiovascular risk profile. However, troglitazone, the first compound approved by the FDA in the US, proved to b...
متن کاملOn the Fluid Retention Properties of Shales
The development of engineering activities involving shales such as the extraction of shale gas and shale oil, the nuclear waste geological storage and the sequestration of CO2, has led to an increasing interest toward the geomechanical behaviour of this geomaterial. In the context of such engineering applications, a deep understanding of the hydro-mechanical behaviour of shales is of primary si...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kidney International
سال: 2007
ISSN: 0085-2538
DOI: 10.1038/sj.ki.5002442