There is more than chitin synthase in insect resistance to benzoylureas: molecular markers associated with teflubenzuron resistance in Spodoptera frugiperda

Chitin synthesis inhibitors are successfully used in pest control and an excellent option for integrated management programs due to their low non-target effects. However, field-evolved resistance of lepidopteran pests chitin the selection laboratory-resistant strains these products has been already reported. Therefore, support efficient it is necessary expand knowledge on mechanisms potential molecular markers that detect resistant alleles. Teflubenzuron a inhibitor world widely distributed fall armyworm, Spodoptera frugiperda (J.E. Smith, 1797) (Lepidoptera: Noctuidae). Here, we report inheritance characterization S. strain teflubenzuron. We also evaluated cross-resistance other chitin-synthesis identified single nucleotide polymorphisms (SNPs), which can be as monitoring evolution The selected teflubenzuron was characterized polygenic, autosomal, incompletely recessive. ratio observed nearly 1,365-fold. Teflubenzuron-resistant showed lufenuron novaluron, but not chlorfluazuron. detected set 72 SNPs could frequency field populations. Our data contribute understanding benzoylureas. with candidate tools emergence spread frugiperda.