Therapeutic monitoring of antiepileptic drugs, part I - general principles, "old" antiepileptics
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چکیده
منابع مشابه
Therapeutic drug monitoring of antiepileptic drugs.
Commonly used conventional antiepileptic drugs for pharmacotherapy in epilepsy are phenytoin, carbamazepine and valproic acid. These drugs have complex pharmacokinetic properties leading to fluctuation in their plasma level at given same therapeutic dose. The present study was done to monitor their plasma levels. A prospective observational study was conducted at National Public Health Laborato...
متن کاملTherapeutic monitoring of antiepileptic drugs for epilepsy.
BACKGROUND The aim of drug treatment for epilepsy is to prevent seizures without causing adverse effects. To achieve this, drug dosages need to be individualised. Measuring antiepileptic drug levels in body fluids (therapeutic drug monitoring) is frequently used to optimise drug dosage for individual patients. OBJECTIVES To review the evidence regarding the effects of therapeutic drug monitor...
متن کاملISLAMIC MEDICAL JURISPRUDENCE PART I: GENERAL ASPEC TS AND PRINCIPLES
Islamic medical jurisprudence, which is the subjectconcemed with the application of Islamic laws to the area of medicine, has never been discussed as an independent field of jurisprudence, although several selected topics, especially those concerning food and beverages, sexuality, death, wounds and injuries, and doctor-patient relations have been more discussed than others. The results of a...
متن کاملTherapeutic drug monitoring of antiepileptic drugs by use of saliva.
Blood (serum/plasma) antiepileptic drug (AED) therapeutic drug monitoring (TDM) has proven to be an invaluable surrogate marker for individualizing and optimizing the drug management of patients with epilepsy. Since 1989, there has been an exponential increase in AEDs with 23 currently licensed for clinical use, and recently, there has been renewed and extensive interest in the use of saliva as...
متن کاملPart I General Principles of Cell Death
1 ,2 Several months later, one of the key genes governing the commitment to apoptosis in Caenorhabditis elegans – CED3 – was demonstrated to show homology with ICE.3 These publications initiated a successful search by many groups over the ensuing years for mammalian ICE homologs that should govern cell death. Today these proteases are known as caspases.4 Of the 11 caspases in humans, 7 are cons...
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ژورنال
عنوان ژورنال: Klinická farmakologie a farmacie
سال: 2016
ISSN: 1212-7973,1803-5353
DOI: 10.36290/far.2016.013