Therapeutic hypothermia in global cerebral ischemia after renewed cardiopulmonary resuscitation guidelines
نویسندگان
چکیده
منابع مشابه
Cardiopulmonary Cerebral Resuscitation: Current Guidelines
Cardiopulmonary cerebral resuscitation (CPCR) refers to the re-establishment of circulation and preservation of neurologic function following an arrest. Since its inception in the late 1800’s, CPCR has saved the lives of countless human and veterinary patients. However, low overall survival rates following CPCR indicate that there is still much room for improvement in these practices. This sess...
متن کاملProspects for Mild Therapeutic Hypothermia and Improved CPR in Cardiopulmonary Cerebral Resuscitation
Each year in the United States there are ~450,00 deaths from myocardial infarction (MI) [1] (with 310,000of these deaths occurring before the patient reaches the hospital) as a result of a non-perfusing arrhythmia, principally ventricular fibrillation.[2] This mode of sudden cardiac arrest (SCA) is also responsible for the majority of the 190,000 in-hospital deaths from MI, which typically occu...
متن کاملMild hypothermia reduces expression of Fas/FasL and MMP-3 after cerebral ischemia-reperfusion in rats
Objective(s):To investigate the effects of local mild hypothermia on the expression of Fas, FasL and MMP-3 after cerebral ischemia-reperfusion in rats. Materials and Methods:Male Wistar rats were divided into sham-operated group (Sham), normothermia group (NT), and hypothermia group (HT). MCAO/R model was established by Longa’s method, and reperfusion was allowed after 2 hr occlusion. Mild hypo...
متن کاملHypothermia for neuroprotection in adults after cardiopulmonary resuscitation.
BACKGROUND Good neurologic outcome after cardiac arrest is hard to achieve. Interventions during the resuscitation phase and treatment within the first hours after the event are critical. Experimental evidence suggests that therapeutic hypothermia is beneficial, and a number of clinical studies on this subject have been published. OBJECTIVES We performed a systematic review and meta-analysis ...
متن کاملEffects of mild hypothermia on expression of NF-E2-related factor 2 and heme-oxygenase-1 in cerebral cortex and hippocampus after cardiopulmonary resuscitation in rats
Objective(s): The aim of this study was to investigate the effects of mild hypothermia on expression of NF-E2-related factor 2 (Nrf2) and heme-oxygenase-1 (HO-1) of rat cerebral cortex and hippocampus after cardiopulmonary resuscitation and further investigate the possible mechanism of action. Material and Methods:To copy an asphyxia heart arrest model, Sprague Dawley rats were randomly divided...
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ژورنال
عنوان ژورنال: Turkish Journal of Cerebrovascular Diseases
سال: 2011
ISSN: 2146-9113
DOI: 10.5505/tbdhd.2011.42713