Therapeutic efficacy of isavuconazole in experimental Aspergillus fumigatus endophthalmitis
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چکیده
منابع مشابه
Therapeutic efficacy of isavuconazole in experimental Aspergillus fumigatus endophthalmitis
Conclusion. Our findings suggest that the model can reasonably identify patients whose infections would be likely to be covered by cefazolin. Further, the majority of patients would have been covered by a narrower spectrum antibiotics than what they received. Research reported in this publication was supported by the National Institute of Allergy and Infectious Diseases of the NIH under Award N...
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Azole resistance is an emerging problem in Aspergillus fumigatus which translates into treatment failure. Alternative treatments with new azoles may improve therapeutic outcome in invasive aspergillosis (IA) even for strains with decreased susceptibility to current azoles. The in vivo efficacy of 0.25, 1, 4, 16, 64, 128, 256, and 512 mg/kg of body weight/day prodrug isavuconazonium sulfate (BAL...
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We present a case of Aspergillus fumigatus endophthalmitis complicated by necrotizing scleritis in a 68-year-old man with diet-controlled diabetes, after retinal detachment repair. He was initially treated with systemic steroids for surgically induced necrotizing scleritis following routine pars plana vitrectomy. An additional diagnosis of endophthalmitis was made when the patient developed a h...
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A case is reported of bilateral aspergillus endophthalmitis in an infant without any detectable systemic predisposition or focus of infection. The patient is the youngest recorded case of endogenous aspergillus endophthalmitis so far, with an onset of symptoms at the age of 15 days. After histopathological confirmation of the aetiology by enucleation of the atrophic eye, systemic amphotericin B...
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Aspergillus fumigatus remains a major respiratory pathogen in birds. In poultry, infection by A. fumigatus may induce significant economic losses particularly in turkey production. A. fumigatus develops and sporulates easily in poor quality bedding or contaminated feedstuffs in indoor farm environments. Inadequate ventilation and dusty conditions increase the risk of bird exposure to aerosolize...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2017
ISSN: 2328-8957
DOI: 10.1093/ofid/ofx163.633