Therapeutic effectiveness of frozen platelet concentrates for transfusion

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Therapeutic effectiveness of frozen platelet concentrates for transfusion.

Six patients received platelet concentrate transfusions from their HLA-identical siblings. Platelet concentrates were administered either fresh, or after being frozen in 10% dimethylsulfoxide, at a slow controlled rate (1 degree C/min) or rapidly (approximately 8 degrees C/min) in the vapor-phase of a liquid nitrogen refrigerator. The median freeze-thaw loss was 13.5%. The mean 1-hr and 20-hr c...

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(unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request pe...

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ژورنال

عنوان ژورنال: Blood

سال: 1981

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v57.2.243.243