Therapeutic Effect of Melatonin in Experimental Uveitis
نویسندگان
چکیده
منابع مشابه
Melatonin as a therapeutic tool in ophthalmology: implications for glaucoma and uveitis.
Several lines of evidence support the view that increased free radical generation and altered nitric oxide (NO) metabolism play a role in the pathogenesis of highly prevalent ocular diseases, such as glaucoma and uveitis. Data are discussed indicating that melatonin, being an efficient antioxidant that displays antinitridergic properties, has a promising role in the treatment of these ocular dy...
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Melatonin is a methoxyindole synthesized within the pineal gland. The hormone is secreted during the night and appears to play multiple roles within the human organism. The hormone contributes to the regulation of biological rhythms, may induce sleep, has strong antioxidant action and appears to contribute to the protection of the organism from carcinogenesis and neurodegenerative disorders. At...
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In humans, N-acetyl-5-methoxytryptamine (melatonin), a neurohormone widely found in plants and animal sources, is synthesized from serotonin primarily by the pineal gland. However, it it is also produced in a number of other areas, e.g. the gastrointestinal tract. Melatonin regulates various biological and physiologic body functions and its role in the regulation of circadian rhythms, particula...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2008
ISSN: 0002-9440
DOI: 10.2353/ajpath.2008.080518