Therapeutic Applications of Extracellular Matrix

EXTRACELLULAR VESICLES AND THEIR THERAPEUTIC APPLICATIONS: A REVIEW

Background & Aims: Extracellular vesicles are double phospholipid layer vesicles releasing from several cells.  These particles contain bio-molecules including mRNA, miRNA, DNA, proteins, and lipids which play a pivotal role in the cell to cell communication. Once delivered, they participate to change target cell function, fate, morphology, differentiation, and growth. The present study is a re...

Mining the extracellular matrix for tissue engineering applications.

Tissue engineering is a rapidly evolving interdisciplinary field that aims to regenerate new tissue to replace damaged tissues or organs. The extracellular matrix (ECM) of animal tissues is a complex mixture of macromolecules that play an essential instructional role in the development of tissues and organs. Therefore, tissue engineering approaches rely on the need to present the correct cues t...

Extracellular Matrix

The tissues of a multicellular organism contain two main components, the cells themselves, onwhichmost biological research has traditionally focused, and the material that lies between the cells. This material is called the extracellular matrix, usually abbreviated to ‘ECM’. The ratio of tissue volume occupied by ECM to that occupied by cells varies from less than 1:10 (e.g. in muscles) to more...

Editorial: Brain Extracellular Space: Geometry, Matrix and Physiological Importance

On Conditional Applications of Matrix Variate Normal Distribution

In this paper, by conditioning on the matrix variate normal distribution (MVND) the construction of the matrix t-type family is considered, thus providing a new perspective of this family. Some important statistical characteristics are given. The presented t-type family is an extension to the work of Dickey [8]. A Bayes estimator for the column covariance matrix &Sigma of MVND is derived under ...