Theophylline, epinephrine, and neostigmine facilitation of neuromuscular transmission.
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چکیده
منابع مشابه
Theophylline, epinephrine, and neostigmine facilitation of neuromuscular transmission.
Epinephrine can enhance transmission under certain conditions in both the central and peripheral portions of the nervous system.'-6 Increased quantities of acetylcholine are released in response to epinephrine at ganglionic and neuromuscular junctions.4, s At the biochemical level, epinephrine stimulates the formation of adenosine 3',5'-phosphate (cyclic AMP) by preparations of many tissues, an...
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Facilitation in neuromuscular junction of frog, i. e. successive enhancement of muscle action potential by repetitive stimulation, has been considered to be due to the recruitment of numbers of muscle fibres excited through junctions. It has been generally accepted that no neuromuscular facilitation is observed in the mammalian junctions (BROWN and HARVEY, 1941), except in curarized or fatigued...
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The tetanic and single twitch responses of the adductor pollicis muscle were used to study the neuromuscular effects of neostigmine in 26 patients anaesthetized with thiopentone and nitrous oxide. Neostigmine 2.5 mg i.v. given 5 min after exposure to halothane antagonized non-depolarizing neuromuscular block, whereas a second dose give 2-5 min later depressed the peak tetanic contraction and re...
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1. A quantitative description of facilitation in the crayfish claw opener muscle is presented. The facilitation of a test response following one or more conditioning stimuli, and the growth of facilitation during a tetanus, are measured. 2. In superficial central fibres facilitation following one or more impulses can be described as the sum of two components which are both maximum at the end of...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1967
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.57.6.1893