The Xpert MTB/RIF assay: A game-changer, but not infallible

The game changer.

wants to make the transition between medical school and residency seamless. A lthough she no longer heads a medical school, Deborah Powell is making a mark on medical education. She's trying to break down the wall between medical school and residency and wants to see students trained in a way that's practical , efficient and better reflects the way medicine is practiced today. " Medicine has ev...

Graphene: the game changer?

C 2012 American Chemical Society Graphene: The Game Changer? I t has only been eight years since the isolation of graphene 1 and over a year since the 2010 Nobel Prize in Physics was jointly awarded to Andre Geim and Konstantin Novoselov “for groundbreaking experiments regarding the two-dimensional material graphene.” Nevertheless, the number of graphene publications is still rapidly growing. T...

Immunotherapy for Lung Cancer – a Game Changer!

GeneXpert—A Game-Changer for Tuberculosis Control?

Tuberculosis (TB) kills more people than any other single infection, the global burden of TB cases and drug resistance are increasing [1], and most patients still only have access to an inadequate diagnostic test developed more than a century ago. Recent evaluations of a desktop machine called the GeneXpert MTB/ RIF that in less than two hours simultaneously detects Mycobacterium tuberculosis a...

Metagenomics: The Next Culture-Independent Game Changer

A trend towards the abandonment of obtaining pure culture isolates in frontline laboratories is at a crossroads with the ability of public health agencies to perform their basic mandate of foodborne disease surveillance and response. The implementation of culture-independent diagnostic tests (CIDTs) including nucleic acid and antigen-based assays for acute gastroenteritis is leaving public heal...