The virtual assay software for human in silico drug trials to augment drug cardiac testing

• Human in silico drug trials improve early predictions of drug-induced adverse cardiac events. Translation process from academic methodology to software for pharma industry. Key milestones a successful translation Prediction effects on the heart still represents challenge development, given potential outcomes. Computer modelling and simulations human offer powerful technology augment existing animal clinical methodologies. Here we describe that led development uptake Virtual Assay, user-friendly perform population models. Through this work, contributed industry regulatory paradigms, demonstrated accurate mechanistic pro-arrhythmic toxicity.