The type 1 pili regulator gene fimX and pathogenicity island PAI-X as molecular markers of uropathogenic Escherichia coli
نویسندگان
چکیده
منابع مشابه
The pathogenicity islands (PAIs) of the uropathogenic Escherichia coli strain 536: island probing of PAI II536.
Pathogenicity islands (PAIs) represent distinct pieces of DNA that are present in the genomes of pathogenic bacteria but absent from the genomes of related nonpathogenic strains. They carry (often more than one) virulence genes and are linked to transfer RNA (tRNA) loci. In addition, they carry mobility genes and direct repeats at their ends and are often unstable [1]. The first PAIs have been ...
متن کاملMolecular Characterization and Antimicrobial Resistance of Uropathogenic Escherichia coli
Background:Urinary Tract Infections (UTIs) are the most common infectious diseases in childhood. The Uropathogenic Escherichia coli (UPEC) strains account for as much as 80% of UTIs. Objective:From a clinical perspective, it is important to know which virulence factors and antibiotic resistance properties are present in UPEC strains in pediatrics. Therefore, this study was carried out...
متن کاملdistribution of the pathogenicity island (pai) markers and phylogenetic groups in diarrheagenic and commensal escherichia coli from young children
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متن کاملHuman Urine Decreases Function and Expression of Type 1 Pili in Uropathogenic Escherichia coli
UNLABELLED Uropathogenic Escherichia coli (UPEC) is the primary cause of community-acquired urinary tract infections (UTIs). UPEC bind the bladder using type 1 pili, encoded by the fim operon in nearly all E. coli. Assembled type 1 pili terminate in the FimH adhesin, which specifically binds to mannosylated glycoproteins on the bladder epithelium. Expression of type 1 pili is regulated in part ...
متن کاملDevelopment of intracellular bacterial communities of uropathogenic Escherichia coli depends on type 1 pili.
Uropathogenic Escherichia coli, the predominant causative agent of urinary tract infections, use type 1 pili to bind and invade bladder epithelial cells. Upon entry, the bacteria rapidly replicate and enter a complex developmental pathway ultimately forming intracellular bacterial communities (IBCs), a niche with biofilm-like properties protected from innate defences and antibiotics. Paradoxica...
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ژورنال
عنوان ژورنال: Microbiology
سال: 2013
ISSN: 1350-0872,1465-2080
DOI: 10.1099/mic.0.066472-0