The treatment of Wilms' Tumor: Results of the second national Wilms' Tumor study

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Treatment of Wilms' tumor. Results of the Third National Wilms' Tumor Study.

The Third National Wilms' Tumor Study sought to reduce treatment for low-risk patients and find better chemotherapy for those at high risk for relapse. Eligible patients (1439) were randomized according to stage (I-IV) and histology (favorable [FH] or unfavorable [UH]), and contributed data to survival and relapse-free survival (RFS) analyses. Four-year (postnephrectomy) survival percentages an...

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The management of synchronous bilateral Wilms tumor: a report from the National Wilms Tumor Study Group.

OBJECTIVE To provide guidelines for future trials, we reviewed the outcomes of children with synchronous bilateral Wilms tumors (BWT) treated on National Wilms Tumor Study-4 (NWTS-4). METHODS NWTS-4 enrolled 3335 patients including 188 patients with BWT (5.6%). Treatment and outcome data were collected. RESULTS Among 188 BWT patients registered with NWTS-4, 195 kidneys in 123 patients had i...

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Age distribution of Wilms' tumor: report from the National Wilms' Tumor Study.

Median ages at diagnosis were 36.5 and 42.5 mo for 1523 males and 1678 females with unilateral Wilms' tumor registered between October 1969 and December 1985; they were 23.5 mo and 30.5 mo for 100 males and 141 females with bilateral disease. The median age for multicentric, unilateral cases was intermediate between the bilateral and unicentric medians. Patients with hemihypertrophy in addition...

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MiR-21 Expression in Wilms’ Tumor

Background and Objective: Wilms’ tumor (WT) is the most common genitourinary tract tumor in children. MicroRNAs (miRNAs) are small non-coding RNAs; their role in the pathogenesis of many types of human cancers has been identified. We aimed to evaluate the expression of miR-21, a well-known oncomir, in WT tissue samples which is a very common urinary tract malignancy in children...

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Wilms' tumor of the ovary

Extrarenal Wilms' tumor of the ovary is a very rare tumor likely derived from embryonic mesonephros. We present the first reported case of a teratoid extrarenal Wilms' tumor of the ovary with a short review of the existing literature. In the case, a 26-year-old woman presented with back pain and was found to have a dermoid cyst; three years later, she presented again, now pregnant, with severe ...

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ژورنال

عنوان ژورنال: Cancer

سال: 1981

ISSN: 0008-543X,1097-0142

DOI: 10.1002/1097-0142(19810501)47:9<2302::aid-cncr2820470933>3.0.co;2-k