The treatment of falciparum malaria in children with halofantrine suspension

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Halofantrine in the treatment of falciparum malaria.

50 patients (45 males + 5 females) suffering from acute uncomplicated attack of Plasmodium falciparum (Pf) malaria were treated with 1500 mg of halofantrine divided in three doses of 500 mg each given at an interval of 6 h. Results showed there were no primary treatment failures. Average Parasite Clearance Time (av. PCT) was 51.12 h and average Fever Clearance Time (av. FCT) was 31.25 h. Advers...

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Halofantrine Treatment of acute Plasmodium falciparum malaria in infants and young children

Introduction Malaria in very young children is a major therapeutic challenge in highly endemic areas where initial infection can occur in the first few months of life. Because active immunity has not begun to be established, infants are most at risk from falciparum malaria, and it has been estimated by the World Health Organisation that up to 1096 of all infant mortality in Africa is directly o...

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Efficacy of halofantrine in malaria.

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ژورنال

عنوان ژورنال: Memórias do Instituto Oswaldo Cruz

سال: 1992

ISSN: 0074-0276

DOI: 10.1590/s0074-02761992000700044