The therapeutic potential of skin mucus from Asian swamp eel (Monopterus albus): In vivo evaluation and histological evidence
نویسندگان
چکیده
The Asian swamp eel (Monopterus albus), is commonly distributed in countries. However, its therapeutic potential has not been thoroughly investigated yet. current study aimed to evaluate the in-vivo properties of skin mucus this fish. was collected fleshly and topical gel with carbopol 934 formulated antibacterial activity on infected rats. Sprague Dawley rats were used divided into 4 groups negative, positive, normal control, treated groups. Intracutaneous injections pathogenic bacteria (Streptococcus pyogenes, Staphylococcus aureus) fungi (Microsporum gypseum, Candida albicans) injected development tinea capitis, impetigo, cutaneous candidiasis animal model confirmed based clinical histopathological observations. To treat rats, a applied rat’s skins topically. histological analysis confirms complete recovery tissues similar commercial antifungal agents positive control present novel an efficient candidate treating infections associated microbes.
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ژورنال
عنوان ژورنال: Journal of King Saud University - Science
سال: 2022
ISSN: ['1018-3647', '2213-686X']
DOI: https://doi.org/10.1016/j.jksus.2022.102011