The Synthetic Adiponectin Receptor Agonist AdipoRon Attenuates Impairment of Cardiac Function Associated with Cardiopulmonary Bypass-induced Systemic Inflammatory Response Syndrome
نویسندگان
چکیده
منابع مشابه
Systemic inflammatory response syndrome after cardiac surgery under cardiopulmonary bypass.
OBJECTIVE This prospective study was designed to elucidate the duration of systemic inflammatory response syndrome (SIRS) and the mechanisms that lead to the protraction of SIRS in patients who are operated on under cardiopulmonary bypass (CPB). METHODS The duration of SIRS in 13 patients with SIRS was studied. Two groups were divided according to the duration to investigate the meaning of th...
متن کامل[Clinical profile of systemic inflammatory response after pediatric cardiac surgery with cardiopulmonary bypass].
BACKGROUND the postoperative period of congenital cardiomyopathies correction is frequently accompanied by systemic inflammatory response. OBJECTIVE To assess the frequency of occurrence and clinical manifestations of the systemic inflammatory response syndrome after cardiopulmonary bypass (SIRS-CPB) in children submitted to cardiac surgery. METHODS Historical cohort study including patient...
متن کاملThe effect of methylprednisolone treatment on the cardiopulmonary bypass-induced systemic inflammatory response.
OBJECTIVE Cardiac surgery with cardiopulmonary bypass (CPB) is associated with an inflammatory response caused by contact of blood with artificial surfaces of the extracorporeal circuit, ischemia-reperfusion injury, and release of endotoxin. The inflammatory reaction involves activation of complement leucocytes, and endothelial cells with secretion of cytokines, proteases, arachidonic acid meta...
متن کاملSystemic inflammatory response syndrome (SIRS) following emergency cardiopulmonary bypass: a case report and literature review.
A complication of emergency resuscitation is the development of the Systemic Inflammatory Response Syndrome (SIRS). In the past, this has been identified as multiple organ failure, with symptoms similar to sepsis. The hallmark of this syndrome is peripheral vasodilation, which is associated with a breakdown of capillary membranes and the accumulation of excess interstitial fluid. This case repo...
متن کاملTicagrelor induced systemic inflammatory response syndrome
BACKGROUND Ticagrelor is a reversible and direct-acting oral antagonist of the adenosine diphosphate receptor P2Y12. Possible adenosine-mediated effects of ticagrelor on inflammation are complex and incompletely understood. To our knowledge, ticagrelor-induced systemic inflammatory response syndrome (SIRS) has not yet been described. CASE PRESENTATION We report the case of an 84 years old pat...
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ژورنال
عنوان ژورنال: The Thoracic and Cardiovascular Surgeon
سال: 2018
ISSN: 0171-6425,1439-1902
DOI: 10.1055/s-0038-1627884