The Synaptonemal Complex Component C(2)M Regulates Meiotic Crossing over in Drosophila
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منابع مشابه
The Synaptonemal Complex Component C(2)M Regulates Meiotic Crossing over in Drosophila
BACKGROUND The synaptonemal complex (SC) is a proteinaceous structure that forms between homologously paired meiotic chromosomes. Previous studies have suggested that the SC is required for meiotic crossing over in Drosophila. However, only one component of this structure, C(3)G, has been identified in Drosophila. RESULTS Mutations in c(2)M cause a reduced frequency of meiotic crossing over d...
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A combined light- and electron-microscopic examination of chromosomes from two angiospermous plants, Plantago ovata and Lycopersicon esculentum, and a mammal, Mus musculus, was performed. From this investigation three observations have been made that may be relevant to the observed lack of crossing over in heterochromatin. (1) Differential staining indicates that heterochromatin represents a sm...
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متن کاملCentral region component1, a novel synaptonemal complex component, is essential for meiotic recombination initiation in rice.
In meiosis, homologous recombination entails programmed DNA double-strand break (DSB) formation and synaptonemal complex (SC) assembly coupled with the DSB repair. Although SCs display extensive structural conservation among species, their components identified are poorly conserved at the sequence level. Here, we identified a novel SC component, designated central region component1 (CRC1), in r...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2003
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(03)00050-2